Anti-BCAP31 antibody (151-200 aa) (STJ91816)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human BAP31 at the amino acid range 151-200
General Information
| Short Description | Rabbit polyclonal anti-B-cell receptor-associated protein 31 (151-200 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BCAP31 |
| Gene ID | 10134 |
| Uniprot ID | BAP31_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human BAP31 at the amino acid range 151-200 |
| Immunogen Region | 151-200 aa |
| Specificity | BAP31 Polyclonal Antibody detects endogenous levels of BAP31 protein. |
Additional Info
| Post Translational Modifications | Cleaved by CASP8 and other caspases. |
| Function | Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40. In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2. May be involved in CASP8-mediated apoptosis. |
| Protein Name | B-Cell Receptor-Associated Protein 31Bcr-Associated Protein 31Bap316c6-Ag Tumor-Associated AntigenProtein CdmP28 |
| Database Links | Reactome: R-HSA-111465Reactome: R-HSA-75153Reactome: R-HSA-8980692Reactome: R-HSA-983170Reactome: R-HSA-9833110 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneMay Shuttle Between The Er And The Intermediate Compartment/Cis-Golgi ComplexAssociates With The Mitochondria-Associated Endoplasmic Reticulum Membrane Via Interaction With Tomm40(Microbial Infection) Upon Sv40 InfectionColocalizes With Dnajc18Dnajb12 And Dnajb14 In Punctate Structures Within The Endoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-B-Cell Receptor-Associated Protein 31 antibodyAnti-Bcr-Associated Protein 31 antibodyAnti-Bap31 antibodyAnti-6c6-Ag Tumor-Associated Antigen antibodyAnti-Protein Cdm antibodyAnti-P28 antibodyAnti-BCAP31 antibodyAnti-BAP31 antibodyAnti-DXS1357E antibody |
Information sourced from Uniprot.org