Anti-BAZ2B IP antibody [SAA0244] (STJA0018759)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Bromodomain Adjacent To Zinc Finger Domain Protein 2b antibody for use in ELISA, IF, IP and IP-MS in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IF/IP/IP-MS |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0244 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 0.82 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | BAZ2B |
| Gene ID | 29994 |
| Uniprot ID | BAZ2B_HUMAN |
Additional Info
| Function | Regulatory subunit of the ATP-dependent BRF-1 and BRF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. The BRF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the BRF-5 ISWI chromatin remodeling complex. Chromatin reader protein, which may play a role in transcriptional regulation via interaction with ISWI. Involved in positively modulating the rate of age-related behavioral deterioration. Represses the expression of mitochondrial function-related genes, perhaps by occupying their promoter regions, working in concert with histone methyltransferase EHMT1. |
| Protein Name | Bromodomain Adjacent To Zinc Finger Domain Protein 2bHwalp4 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Bromodomain Adjacent To Zinc Finger Domain Protein 2b antibodyAnti-Hwalp4 antibodyAnti-BAZ2B antibodyAnti-KIAA1476 antibody |
Information sourced from Uniprot.org