| Function | AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGACGTCA-3' and regulates expression of target genes. |
| Protein Name | Basic Leucine Zipper Transcriptional Factor Atf-Like 3B-Atf-321 Kda Small Nuclear Factor Isolated From T-CellsJun Dimerization Protein P21snft |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Basic Leucine Zipper Transcriptional Factor Atf-Like 3 antibodyAnti-B-Atf-3 antibodyAnti-21 Kda Small Nuclear Factor Isolated From T-Cells antibodyAnti-Jun Dimerization Protein P21snft antibodyAnti-BATF3 antibodyAnti-SNFT antibody |
Information sourced from Uniprot.org
