| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BANP (1-260) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BANP |
| Gene ID: |
54971 |
| Uniprot ID: |
BANP_HUMAN |
| Immunogen Region: |
1-260 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BANP (NP_060339.2). |
| Immunogen Sequence: |
MMSEHDLADVVQIAVEDLSP DHPVVLENHVVTDEDEPALK RQRLEINCQDPSIKSFLYSI NQTICLRLDSIEAKLQALEA TCKSLEEKLDLVTNKQHSPI QVPMVAGSPLGATQTCNKVR CAVPGRRQNTIVVKVPGQED SHHEDGESGSEASDSVSSCG QAGSQSIGSNVTLITLNSEE DYPNGTWLGDENNPEMRVRC AIIPSDMLHISTNCRTAEKM ALTLLDYLFHREVQAVSNL |
| Tissue Specificity | Down-regulated in breast cancer cell lines. |
| Function | Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest. |
| Protein Name | Protein BanpBen Domain-Containing Protein 1Btg3-Associated Nuclear ProteinScaffold/Matrix-Associated Region-1-Binding Protein |
| Database Links | Reactome: R-HSA-6804759 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Banp antibodyAnti-Ben Domain-Containing Protein 1 antibodyAnti-Btg3-Associated Nuclear Protein antibodyAnti-Scaffold/Matrix-Associated Region-1-Binding Protein antibodyAnti-BANP antibodyAnti-BEND1 antibodyAnti-SMAR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
