Anti-BAIAP3 antibody (248-298 aa) (STJ194618)

SKU:
STJ194618
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-BAI1-associated protein 3 (248-298 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:BAIAP3
Gene ID:8938
Uniprot ID:BAIP3_HUMAN
Immunogen:Synthesized peptide derived from the human BAIP3 at the amino acid range 248-298
Immunogen Region:248-298 aa
Specificity:This antibody detects endogenous levels of BAIP3 at Human/Mouse
Function Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin. Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission.
Protein Name Bai1-Associated Protein 3
Bap3
Brain-Specific Angiogenesis Inhibitor I-Associated Protein 3
Database Links
Cellular Localisation Cytoplasm
Cytosol
Recycling Endosome Membrane
Peripheral Membrane Protein
Late Endosome Membrane
Golgi Apparatus
Trans-Golgi Network Membrane
Cell Membrane
Rapidly Recruited To The Plasma Membrane And To Golgi Structures In Response To Increased Intracellular Calcium Concentration
Alternative Antibody Names Anti-Bai1-Associated Protein 3 antibody
Anti-Bap3 antibody
Anti-Brain-Specific Angiogenesis Inhibitor I-Associated Protein 3 antibody
Anti-BAIAP3 antibody
Anti-KIAA0734 antibody

Information sourced from Uniprot.org