Anti-BAIAP3 antibody (248-298 aa) (STJ194618)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human BAIP3 at the amino acid range 248-298
General Information
| Short Description | Rabbit polyclonal anti-BAI1-associated protein 3 (248-298 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BAIAP3 |
| Gene ID | 8938 |
| Uniprot ID | BAIP3_HUMAN |
| Immunogen | Synthesized peptide derived from the human BAIP3 at the amino acid range 248-298 |
| Immunogen Region | 248-298 aa |
| Specificity | This antibody detects endogenous levels of BAIP3 at Human/Mouse |
Additional Info
| Function | Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin. Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission. |
| Protein Name | Bai1-Associated Protein 3Bap3Brain-Specific Angiogenesis Inhibitor I-Associated Protein 3 |
| Database Links | |
| Cellular Localisation | CytoplasmCytosolRecycling Endosome MembranePeripheral Membrane ProteinLate Endosome MembraneGolgi ApparatusTrans-Golgi Network MembraneCell MembraneRapidly Recruited To The Plasma Membrane And To Golgi Structures In Response To Increased Intracellular Calcium Concentration |
| Alternative Antibody Names | Anti-Bai1-Associated Protein 3 antibodyAnti-Bap3 antibodyAnti-Brain-Specific Angiogenesis Inhibitor I-Associated Protein 3 antibodyAnti-BAIAP3 antibodyAnti-KIAA0734 antibody |
Information sourced from Uniprot.org