Anti-BAG4 antibody (355-369 aa) [R06-6J7] (STJA0011961)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human Silencer of Death Domain
General Information
| Short Description | Rabbit monoclonal anti-SODD (355-369 aa) for use in WB, IHC-F, IHC-P, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-6J7 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | 50mM Tris-Glycine (pH7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | BAG4 |
| Gene ID | 9530 |
| Uniprot ID | BAG4_HUMAN |
| Immunogen | A synthetic peptide of human Silencer of Death Domain |
| Immunogen Region | 355-369 aa |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria. |
| Protein Name | Bag Family Molecular Chaperone Regulator 4Bag-4Bcl-2-Associated Athanogene 4Silencer Of Death Domains |
| Database Links | Reactome: R-HSA-3371453Reactome: R-HSA-5655302Reactome: R-HSA-75893Reactome: R-HSA-8853336 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Bag Family Molecular Chaperone Regulator 4 antibodyAnti-Bag-4 antibodyAnti-Bcl-2-Associated Athanogene 4 antibodyAnti-Silencer Of Death Domains antibodyAnti-BAG4 antibodyAnti-SODD antibody |
Information sourced from Uniprot.org