Anti-Baf180 antibody (STJA0037832)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human Baf180
General Information
| Short Description | Rabbit monoclonal anti-Baf180 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PBRM1 |
| Gene ID | 55193 |
| Uniprot ID | PB1_HUMAN |
| Immunogen | Recombinant protein of human Baf180 |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). Acts as a negative regulator of cell proliferation. |
| Protein Name | Protein Polybromo-1Hpb1Brg1-Associated Factor 180Baf180Polybromo-1d |
| Database Links | Reactome: R-HSA-3214858Reactome: R-HSA-8939243 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Protein Polybromo-1 antibodyAnti-Hpb1 antibodyAnti-Brg1-Associated Factor 180 antibodyAnti-Baf180 antibodyAnti-Polybromo-1d antibodyAnti-PBRM1 antibodyAnti-BAF180 antibodyAnti-PB1 antibody |
Information sourced from Uniprot.org