Anti-B4GALNT2 antibody (STJ190605)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Beta-1, 4 N-acetylgalactosaminyltransferase 2 beta-1, 4-GalNAc transferase for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | B4GALNT2 |
| Gene ID | 124872 |
| Uniprot ID | B4GN2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | B4GN2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Beta-1,4 N-acetylgalactosaminyltransferase involved in the biosynthesis of Sd(a) histo-blood group antigen. Catalyzes the transfer of N-acetylgalactosamine (GalNAc) group in a beta-1,4-linkage from UDP-GalNAc to the galactose residue of NeuAcalpha2->3Gal-R to form Sd(a) glycan epitope GalNAcbeta1->4(NeuAcalpha2->3)Gal-R. The Sd(a) epitope is carried in O- and N-linked glycoproteins and glycolipids, including O-linked core 1 structures on GYPA/glycophorin, SLC4A1 and SLC29A1 in erythrocytes, N-linked glycans attached to the Tamm-Horsfall glycoprotein UMOD/uromodulin in renal fluids, O-linked core 3 glycans on mucins in colon and neolactosides in gastric mucosa. Confers protection against influenza A virus strains that attach to NeuAcalpha2->3-carrying host receptors. Modifies N-glycan chains on host receptors and prevents virus entry into cells. |
| Protein Name | Beta-1 -4 N-Acetylgalactosaminyltransferase 2Sd(A Beta-1 -4-Galnac TransferaseUdp-Galnac -Neu5aca2-3galb-R B1 -4-N-Acetylgalactosaminyltransferase |
| Database Links | Reactome: R-HSA-446203Reactome: R-HSA-9037629 |
| Cellular Localisation | Isoform 1: Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Ii Membrane ProteinCytoplasmic Vesicle MembranePartially Colocalizes With Eea1 And Lamp2 In Early Endosomes And LysosomesRespectivelyIsoform 2: Golgi Apparatus |
| Alternative Antibody Names | Anti-Beta-1 -4 N-Acetylgalactosaminyltransferase 2 antibodyAnti-Sd(A Beta-1 -4-Galnac Transferase antibodyAnti-Udp-Galnac -Neu5aca2-3galb-R B1 -4-N-Acetylgalactosaminyltransferase antibodyAnti-B4GALNT2 antibodyAnti-GALGT2 antibody |
Information sourced from Uniprot.org