| Function | Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer.paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development. |
| Protein Name | Lactosylceramide 1 -3-N-Acetyl-Beta-D-GlucosaminyltransferaseLactotriaosylceramide SynthaseLc(3cer SynthaseLc3 SynthaseUdp-Glcnac -Beta-Gal Beta-1 -3-N-Acetylglucosaminyltransferase 5Bgnt-5Beta-1 -3-Gn-T5Beta-1 -3-N-Acetylglucosaminyltransferase 5Beta3gn-T5 |
| Database Links | Reactome: R-HSA-913709Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Lactosylceramide 1 -3-N-Acetyl-Beta-D-Glucosaminyltransferase antibodyAnti-Lactotriaosylceramide Synthase antibodyAnti-Lc(3cer Synthase antibodyAnti-Lc3 Synthase antibodyAnti-Udp-Glcnac -Beta-Gal Beta-1 -3-N-Acetylglucosaminyltransferase 5 antibodyAnti-Bgnt-5 antibodyAnti-Beta-1 -3-Gn-T5 antibodyAnti-Beta-1 -3-N-Acetylglucosaminyltransferase 5 antibodyAnti-Beta3gn-T5 antibodyAnti-B3GNT5 antibody |
Information sourced from Uniprot.org
