Anti-B3GAT1 antibody [IHC539] (STJA0041993)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgM
ImmunogenHuman CD57 protein.
General Information
| Short Description | Mouse monoclonal anti-B3GAT1 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC539 |
| Isotype | IgM |
| Conjugation | Unconjugated |
| Dilution Range | 1:100-1:200 |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Gene Symbol | B3GAT1 |
| Gene ID | 27087 |
| Uniprot ID | B3GA1_HUMAN |
| Immunogen | Human CD57 protein. |
| Specificity | Tested and validated on tonsil tissue. |
Additional Info
| Tissue Specificity | Mainly expressed in the brain. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Protein Name | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1Beta-1 -3-Glucuronyltransferase 1Glucuronosyltransferase PGlcat-PUdp-Glcua -Glycoprotein Beta-1 -3-GlucuronyltransferaseGlcuat-P |
| Database Links | Reactome: R-HSA-1971475 |
| Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedIsoform 2: Golgi Apparatus MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 antibodyAnti-Beta-1 -3-Glucuronyltransferase 1 antibodyAnti-Glucuronosyltransferase P antibodyAnti-Glcat-P antibodyAnti-Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase antibodyAnti-Glcuat-P antibodyAnti-B3GAT1 antibodyAnti-GLCATP antibody |
Information sourced from Uniprot.org