Anti-AVP antibody (20-164) (STJ117784)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal AVP (20-164) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AVP |
| Gene ID | 551 |
| Uniprot ID | NEU2_HUMAN |
| Immunogen Region | 20-164 |
| Immunogen Sequence | CYFQNCPRGGKRAMSDLELR QCLPCGPGGKGRCFGPSICC ADELGCFVGTAEALRCQEEN YLPSPCQSGQKACGSGGRCA AFGVCCNDESCVTEPECREG FHRRARASDRSNATQLDGPA GALLLRLVQLAGAPEPFEPA QPDAY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-164 of human AVP (NP_000481.2). |
Additional Info
| Function | Neurophysin 2: Specifically binds vasopressin. Arg-vasopressin: Has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2). |
| Protein Name | Vasopressin-Neurophysin 2-CopeptinAvp-Npii Cleaved Into - Arg-VasopressinArginine-Vasopressin - Neurophysin 2Neurophysin-Ii - Copeptin |
| Database Links | Reactome: R-HSA-1368108Reactome: R-HSA-388479Reactome: R-HSA-416476Reactome: R-HSA-418555Reactome: R-HSA-432040Reactome: R-HSA-5619099Reactome: R-HSA-879518Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-9036092 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Vasopressin-Neurophysin 2-Copeptin antibodyAnti-Avp-Npii Cleaved Into - Arg-Vasopressin antibodyAnti-Arginine-Vasopressin - Neurophysin 2 antibodyAnti-Neurophysin-Ii - Copeptin antibodyAnti-AVP antibodyAnti-ARVP antibodyAnti-VP antibody |
Information sourced from Uniprot.org