| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATXN10 (346-475) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATXN10 |
| Gene ID: |
25814 |
| Uniprot ID: |
ATX10_HUMAN |
| Immunogen Region: |
346-475 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 346-475 of human ATXN10 (NP_037368.1). |
| Immunogen Sequence: |
ETTNIFSNCGCVRAEGDISN VANGFKSHLIRLIGNLCYKN KDNQDKVNELDGIPLILDNC NISDSNPFLTQWVIYAIRNL TEDNSQNQDLIAKMEEQGLA DASLLKKVGFEVEKKGEKLI LKSTRDTPKP |
| Tissue Specificity | Expressed in the central nervous system. |
| Function | Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. |
| Protein Name | Ataxin-10Brain Protein E46 HomologSpinocerebellar Ataxia Type 10 Protein |
| Cellular Localisation | CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Ataxin-10 antibodyAnti-Brain Protein E46 Homolog antibodyAnti-Spinocerebellar Ataxia Type 10 Protein antibodyAnti-ATXN10 antibodyAnti-SCA10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
