• Western blot analysis of various lysates, using ATRIP antibody (STJ11103010) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-ATRIP antibody (200-300) [S0MR] (STJ11103010)

SKU:
STJ11103010

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-ATRIP (200-300) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S0MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATRIP
Gene ID: 84126
Uniprot ID: ATRIP_HUMAN
Immunogen Region: 200-300
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ATRIP (Q8WXE1).
Immunogen Sequence: NELRTKLQTSERANKLAAPS VSHVSPRKNPSVVIKPEACS PQFGKTSFPTKESFSANMSL PHPCQTESGYKPLVGREDSK PHSLRGDSIKQEEAQKSFVD S
Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylated by ATR.
Function Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Protein Name Atr-Interacting Protein
Atm And Rad3-Related-Interacting Protein
Database Links Reactome: R-HSA-176187
Reactome: R-HSA-5685938
Reactome: R-HSA-5693607
Reactome: R-HSA-5693616
Reactome: R-HSA-6783310
Reactome: R-HSA-6804756
Reactome: R-HSA-69473
Reactome: R-HSA-9709570
Cellular Localisation Nucleus
Redistributes To Discrete Nuclear Foci Upon Dna Damage
Alternative Antibody Names Anti-Atr-Interacting Protein antibody
Anti-Atm And Rad3-Related-Interacting Protein antibody
Anti-ATRIP antibody
Anti-AGS1 antibody

Information sourced from Uniprot.org

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