Anti-ATRIP antibody (1-260) (STJ29219)

Name: Anti-ATRIP antibody (1-260) (STJ29219)
SKU: STJ29219
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ29219

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Short Description	Rabbit polyclonal ATRIP (1-260) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ATRIP
Gene ID	84126
Uniprot ID	ATRIP_HUMAN
Immunogen Region	1-260
Immunogen Sequence	MAGTSAPGSKRRSEPPAPRP GPPPGTGHPPSKRARGFSAA AAPDPDDPFGAHGDFTADDL EELDTLASQALSQCPAAARD VSSDHKVHRLLDGMSKNPSG KNRETVPIKDNFELEVLQAQ YKELKEKMKVMEEEVLIKNG EIKILRDSLHQTESVLEEQR RSHFLLEQEKTQALSDKEKE FSKKLQSLQSELQFKDAEMN ELRTKLQTSERANKLAAPSV SHVSPRKNPSVVIKPEACS
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ATRIP (NP_569055.1).

Tissue Specificity	Ubiquitous.
Post Translational Modifications	Phosphorylated by ATR.
Function	Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Protein Name	Atr-Interacting Protein Atm And Rad3-Related-Interacting Protein
Database Links	Reactome: R-HSA-176187 Reactome: R-HSA-5685938 Reactome: R-HSA-5693607 Reactome: R-HSA-5693616 Reactome: R-HSA-6783310 Reactome: R-HSA-6804756 Reactome: R-HSA-69473 Reactome: R-HSA-9709570
Cellular Localisation	Nucleus Redistributes To Discrete Nuclear Foci Upon Dna Damage
Alternative Antibody Names	Anti-Atr-Interacting Protein antibody Anti-Atm And Rad3-Related-Interacting Protein antibody Anti-ATRIP antibody Anti-AGS1 antibody

Information sourced from Uniprot.org