| Short Description : | Rabbit polyclonal anti-All-trans retinoic acid-induced differentiation factor (1-80 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATRAID |
| Gene ID: | 51374 |
| Uniprot ID: | ARAID_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 1-80 |
| Immunogen Region: | 1-80 aa |
| Specificity: | ARAID Polyclonal Antibody detects endogenous levels of protein. |
| Function | Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol. |
| Protein Name | All-Trans Retinoic Acid-Induced Differentiation FactorApoptosis-Related Protein 3Apr-3P18 |
| Database Links | |
| Cellular Localisation | Nucleus EnvelopeCell MembraneSingle-Pass Membrane ProteinLysosome MembraneMulti-Pass Membrane ProteinColocalizes With Nell1 On The Nuclear Envelope And The Perinuclear Region |
| Alternative Antibody Names | Anti-All-Trans Retinoic Acid-Induced Differentiation Factor antibodyAnti-Apoptosis-Related Protein 3 antibodyAnti-Apr-3 antibodyAnti-P18 antibodyAnti-ATRAID antibodyAnti-APR3 antibodyAnti-C2orf28 antibodyAnti-HSPC013 antibodyAnti-UNQ214 antibodyAnti-PRO240 antibody |
Information sourced from Uniprot.org
