Anti-ATP6V1H antibody (341-390 aa) (STJ96226)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ATP6V1H at the amino acid range 341-390
General Information
| Short Description | Rabbit polyclonal anti-V-type proton ATPase subunit H (341-390 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP6V1H |
| Gene ID | 51606 |
| Uniprot ID | VATH_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ATP6V1H at the amino acid range 341-390 |
| Immunogen Region | 341-390 aa |
| Specificity | V-ATPase H Polyclonal Antibody detects endogenous levels of V-ATPase H protein. |
Additional Info
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit H is essential for V-ATPase activity, but not for the assembly of the complex. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes. |
| Protein Name | V-Type Proton Atpase Subunit HV-Atpase Subunit HNef-Binding Protein 1Nbp1Protein Vma13 HomologV-Atpase 50/57 Kda SubunitsVacuolar Proton Pump Subunit HVacuolar Proton Pump Subunit Sfd |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-167590Reactome: R-HSA-182218Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9636467Reactome: R-HSA-9639288Reactome: R-HSA-983712Reactome: R-HSA-9857377 |
| Cellular Localisation | Cytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit H antibodyAnti-V-Atpase Subunit H antibodyAnti-Nef-Binding Protein 1 antibodyAnti-Nbp1 antibodyAnti-Protein Vma13 Homolog antibodyAnti-V-Atpase 50/57 Kda Subunits antibodyAnti-Vacuolar Proton Pump Subunit H antibodyAnti-Vacuolar Proton Pump Subunit Sfd antibodyAnti-ATP6V1H antibodyAnti-CGI-11 antibody |
Information sourced from Uniprot.org