| Short Description : | Rabbit polyclonal ATP6V1G2 (40-100) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATP6V1G2 |
| Gene ID: | 534 |
| Uniprot ID: | VATG2_HUMAN |
| Immunogen Region: | 40-100 |
| Immunogen Sequence: | AQMEVEQYRREREHEFQSKQ QAAMGSQGNLSAEVEQATRR QVQGMQSSQQRNRERVLAQL L |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-100 of human ATP6V1G2 (NP_569730.1). |
| Tissue Specificity | Brain. |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. |
| Protein Name | V-Type Proton Atpase Subunit G 2V-Atpase Subunit G 2V-Atpase 13 Kda Subunit 2Vacuolar Proton Pump Subunit G 2 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | MelanosomeCytoplasmic VesicleClathrin-Coated Vesicle MembranePeripheral Membrane ProteinHighly Enriched In Late-Stage Melanosomes |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit G 2 antibodyAnti-V-Atpase Subunit G 2 antibodyAnti-V-Atpase 13 Kda Subunit 2 antibodyAnti-Vacuolar Proton Pump Subunit G 2 antibodyAnti-ATP6V1G2 antibodyAnti-ATP6G antibodyAnti-ATP6G2 antibodyAnti-NG38 antibody |
Information sourced from Uniprot.org
