| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-V-type proton ATPase subunit G 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATP6V1G1 |
| Gene ID: |
9550 |
| Uniprot ID: |
VATG1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ATP6V1G1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human ATP6V1G1 |
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. |
| Protein Name | V-Type Proton Atpase Subunit G 1V-Atpase Subunit G 1V-Atpase 13 Kda Subunit 1Vacuolar Proton Pump Subunit G 1Vacuolar Proton Pump Subunit M16 |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | Apical Cell Membrane |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit G 1 antibodyAnti-V-Atpase Subunit G 1 antibodyAnti-V-Atpase 13 Kda Subunit 1 antibodyAnti-Vacuolar Proton Pump Subunit G 1 antibodyAnti-Vacuolar Proton Pump Subunit M16 antibodyAnti-ATP6V1G1 antibodyAnti-ATP6G antibodyAnti-ATP6G1 antibodyAnti-ATP6J antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
