Anti-ATP6V1D antibody (1-247) (STJ114806)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ATP6V1D (1-247) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP6V1D |
| Gene ID | 51382 |
| Uniprot ID | VATD_HUMAN |
| Immunogen Region | 1-247 |
| Immunogen Sequence | MSGKDRIEIFPSRMAQTIMK ARLKGAQTGRNLLKKKSDAL TLRFRQILKKIIETKMLMGE VMREAAFSLAEAKFTAGDFS TTVIQNVNKAQVKIRAKKDN VAGVTLPVFEHYHEGTDSYE LTGLARGGEQLAKLKRNYAK AVELLVELASLQTSFVTLDE AIKITNRRVNAIEHVIIPRI ERTLAYIITELDEREREEFY RLKKIQEKKKILKEKSEKDL EQRRAAGEVLEPANLLAEE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-247 of human ATP6V1D (NP_057078.1). |
Additional Info
| Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. |
| Protein Name | V-Type Proton Atpase Subunit DV-Atpase Subunit DV-Atpase 28 Kda Accessory ProteinVacuolar Proton Pump Subunit D |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-6798695Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712 |
| Cellular Localisation | MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmic VesicleClathrin-Coated Vesicle MembraneCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCell ProjectionCiliumLocalizes To Centrosome And The Base Of The Cilium |
| Alternative Antibody Names | Anti-V-Type Proton Atpase Subunit D antibodyAnti-V-Atpase Subunit D antibodyAnti-V-Atpase 28 Kda Accessory Protein antibodyAnti-Vacuolar Proton Pump Subunit D antibodyAnti-ATP6V1D antibodyAnti-ATP6M antibodyAnti-VATD antibody |
Information sourced from Uniprot.org