Anti-ATP6V0B antibody (149-199 aa) (STJ193834)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human VATO at the amino acid range 149-199
General Information
| Short Description | Rabbit polyclonal anti-V-type proton ATPase 21 kDa proteolipid subunit c (149-199 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP6V0B |
| Gene ID | 533 |
| Uniprot ID | VATO_HUMAN |
| Immunogen | Synthesized peptide derived from the human VATO at the amino acid range 149-199 |
| Immunogen Region | 149-199 aa |
| Specificity | This antibody detects endogenous levels of VATO at Human/Mouse |
Additional Info
| Function | Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. |
| Protein Name | V-Type Proton Atpase 21 Kda Proteolipid Subunit C''V-Atpase 21 Kda Proteolipid Subunit C''Vacuolar Proton Pump 21 Kda Proteolipid Subunit C''Hatpl |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-77387Reactome: R-HSA-917977Reactome: R-HSA-9639288Reactome: R-HSA-983712Reactome: R-HSA-9857377 |
| Cellular Localisation | Cytoplasmic VesicleClathrin-Coated Vesicle MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-V-Type Proton Atpase 21 Kda Proteolipid Subunit C'' antibodyAnti-V-Atpase 21 Kda Proteolipid Subunit C'' antibodyAnti-Vacuolar Proton Pump 21 Kda Proteolipid Subunit C'' antibodyAnti-Hatpl antibodyAnti-ATP6V0B antibodyAnti-ATP6F antibody |
Information sourced from Uniprot.org