Anti-ATP5MC1 antibody (Internal) (STJ91768)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the Internal region of human ATP5G1.
General Information
| Short Description | Rabbit polyclonal anti-ATP synthase F0 complex subunit C1, mitochondrial complex subunit C1 (Internal) for use in IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP5MC1 |
| Gene ID | 516 |
| Uniprot ID | AT5G1_HUMAN |
| Immunogen | Synthesized peptide derived from the Internal region of human ATP5G1. |
| Immunogen Region | Internal |
| Specificity | ATP5G1 Polyclonal Antibody detects endogenous levels of ATP5G1 protein. |
Additional Info
| Function | Subunit c, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable). ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). With the subunit a (MT-ATP6), forms the proton-conducting channel in the F(0) domain, that contains two crucial half-channels (inlet and outlet) that facilitate proton movement from the mitochondrial intermembrane space (IMS) into the matrix. Protons are taken up via the inlet half-channel and released through the outlet half-channel, following a Grotthuss mechanism. |
| Protein Name | Atp Synthase F(0 Complex Subunit C1 - MitochondrialAtp Synthase Lipid-Binding ProteinAtp Synthase Membrane Subunit C Locus 1Atp Synthase Proteolipid P1Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit C1Atpase Protein 9Atpase Subunit CProton-Conducting Channel - Atp Synthase F(0 Complex Subunit C |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
| Cellular Localisation | Mitochondrion MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp Synthase F(0 Complex Subunit C1 - Mitochondrial antibodyAnti-Atp Synthase Lipid-Binding Protein antibodyAnti-Atp Synthase Membrane Subunit C Locus 1 antibodyAnti-Atp Synthase Proteolipid P1 antibodyAnti-Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit C1 antibodyAnti-Atpase Protein 9 antibodyAnti-Atpase Subunit C antibodyAnti-Proton-Conducting Channel - Atp Synthase F(0 Complex Subunit C antibodyAnti-ATP5MC1 antibodyAnti-ATP5G1 antibody |
Information sourced from Uniprot.org