Anti-ATP5F1 antibody (1-245) (STJ29959)

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STJ29959
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATP5PB
Gene ID: 515
Uniprot ID: AT5F1_HUMAN
Immunogen Region: 1-245
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human ATP5F1 (NP_001679.2).
Immunogen Sequence: MLSRVVLSAAATAAPSLKNA AFLGPGVLQATRTFHTGQPH LVPVPPLPEYGGKVRYGLIP EEFFQFLYPKTGVTGPYVLG TGLILYALSKEIYVISAETF TALSVLGVMVYGIKKYGPFV ADFADKLNEQKLAQLEEAKQ ASIQHIQNAIDTEKSQQALV QKRHYLFDVQRNNIAMALEV TYRERLYRVYKEVKNRLDYH ISVQNMMRRKEQEHMINWVE KHVVQSISTQQEKETIAKC
Function Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
Protein Name Atp Synthase Peripheral Stalk Subunit B - Mitochondrial
Atp Synthase F(0 Complex Subunit B1 - Mitochondrial
Atp Synthase Peripheral Stalk-Membrane Subunit B
Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit B1
Atp Synthase Subunit B
Atpase Subunit B
Database Links Reactome: R-HSA-163210
Reactome: R-HSA-8949613
Cellular Localisation Mitochondrion
Mitochondrion Inner Membrane
Alternative Antibody Names Anti-Atp Synthase Peripheral Stalk Subunit B - Mitochondrial antibody
Anti-Atp Synthase F(0 Complex Subunit B1 - Mitochondrial antibody
Anti-Atp Synthase Peripheral Stalk-Membrane Subunit B antibody
Anti-Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit B1 antibody
Anti-Atp Synthase Subunit B antibody
Anti-Atpase Subunit B antibody
Anti-ATP5PB antibody
Anti-ATP5F1 antibody

Information sourced from Uniprot.org