| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ATP5F1 (1-245) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATP5PB |
| Gene ID: |
515 |
| Uniprot ID: |
AT5F1_HUMAN |
| Immunogen Region: |
1-245 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human ATP5F1 (NP_001679.2). |
| Immunogen Sequence: |
MLSRVVLSAAATAAPSLKNA AFLGPGVLQATRTFHTGQPH LVPVPPLPEYGGKVRYGLIP EEFFQFLYPKTGVTGPYVLG TGLILYALSKEIYVISAETF TALSVLGVMVYGIKKYGPFV ADFADKLNEQKLAQLEEAKQ ASIQHIQNAIDTEKSQQALV QKRHYLFDVQRNNIAMALEV TYRERLYRVYKEVKNRLDYH ISVQNMMRRKEQEHMINWVE KHVVQSISTQQEKETIAKC |
| Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. |
| Protein Name | Atp Synthase F(0 Complex Subunit B1 - MitochondrialAtp Synthase Peripheral Stalk-Membrane Subunit BAtp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit B1Atp Synthase Subunit BAtpase Subunit B |
| Database Links | Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
| Cellular Localisation | MitochondrionMitochondrion Inner Membrane |
| Alternative Antibody Names | Anti-Atp Synthase F(0 Complex Subunit B1 - Mitochondrial antibodyAnti-Atp Synthase Peripheral Stalk-Membrane Subunit B antibodyAnti-Atp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit B1 antibodyAnti-Atp Synthase Subunit B antibodyAnti-Atpase Subunit B antibodyAnti-ATP5PB antibodyAnti-ATP5F1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
