Anti-ATP2B3 antibody (140-220 aa) (STJ191167)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 140-220
General Information
| Short Description | Rabbit polyclonal anti-Plasma membrane calcium-transporting ATPase 3 (140-220 aa) for use in WB and ELISA in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP2B3 |
| Gene ID | 492 |
| Uniprot ID | AT2B3_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 140-220 |
| Immunogen Region | 140-220 aa |
| Specificity | AT2B3 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals. Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment. May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established. |
| Protein Name | Plasma Membrane Calcium-Transporting Atpase 3Pmca3Plasma Membrane Calcium Atpase Isoform 3Plasma Membrane Calcium Pump Isoform 3 |
| Database Links | Reactome: R-HSA-418359Reactome: R-HSA-5578775Reactome: R-HSA-936837 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPresynaptic Cell MembraneLocalized At Parallel Fiber Terminals |
| Alternative Antibody Names | Anti-Plasma Membrane Calcium-Transporting Atpase 3 antibodyAnti-Pmca3 antibodyAnti-Plasma Membrane Calcium Atpase Isoform 3 antibodyAnti-Plasma Membrane Calcium Pump Isoform 3 antibodyAnti-ATP2B3 antibody |
Information sourced from Uniprot.org