Anti-ATP12A antibody (380-460 aa) (STJ96464)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from ATP1AL1 at the amino acid range 380-460
General Information
| Short Description | Rabbit polyclonal anti-Potassium-transporting ATPase alpha chain 2/K+ ATPase subunit alpha/K+ ATPase subunit alpha (380-460 aa) for use in WB and ELISA in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP12A |
| Gene ID | 479 |
| Uniprot ID | AT12A_HUMAN |
| Immunogen | Synthesized peptide derived from ATP1AL1 at the amino acid range 380-460 |
| Immunogen Region | 380-460 aa |
| Specificity | ATP1AL1 Polyclonal Antibody detects endogenous levels of ATP1AL1 protein. |
Additional Info
| Function | The catalytic subunit of a H(+)/K(+) ATPase and/or Na(+)/K(+) ATPase pump which transports K(+) ions in exchange for Na(+) and/or H(+) ions across the apical membrane of epithelial cells. Uses ATP as an energy source to pump K(+) ions into the cell while transporting Na(+) and/or H(+) ions to the extracellular compartment. Involved in the maintenance of electrolyte homeostasis through K(+) ion absorption in kidney and colon. In the airway epithelium, may play a primary role in mucus acidification regulating its viscosity and clearance. |
| Protein Name | Potassium-Transporting Atpase Alpha Chain 2Hk Alpha 2Non-Gastric H(+/K(+ Atpase Subunit AlphaNon-Gastric Na(+/K(+ Atpase Subunit AlphaProton PumpSodium Pump |
| Database Links | Reactome: R-HSA-936837 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium-Transporting Atpase Alpha Chain 2 antibodyAnti-Hk Alpha 2 antibodyAnti-Non-Gastric H(+/K(+ Atpase Subunit Alpha antibodyAnti-Non-Gastric Na(+/K(+ Atpase Subunit Alpha antibodyAnti-Proton Pump antibodyAnti-Sodium Pump antibodyAnti-ATP12A antibodyAnti-ATP1AL1 antibody |
Information sourced from Uniprot.org