Anti-ATMIN antibody (160-360) (STJ29411)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ATMIN (160-360) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATMIN |
| Gene ID | 23300 |
| Uniprot ID | ATMIN_HUMAN |
| Immunogen Region | 160-360 |
| Immunogen Sequence | HAEKKHKCSKCSNSYGTEWD LKRHAEDCGKTFRCTCGCPY ASRTALQSHIYRTGHEIPAE HRDPPSKKRKMENCAQNQKL SNKTIESLNNQPIPRPDTQE LEASEIKLEPSFEDSCGSNT DKQTLTTPPRYPQKLLLPKP KVALVKLPVMQFSVMPVFVP TADSSAQPVVLGVDQGSATG AVHLMPLSVGTLILGLDSEA C |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human ATMIN (NP_056066.2). |
Additional Info
| Tissue Specificity | Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle. |
| Function | Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription. |
| Protein Name | Atm InteractorAtm/Atr-Substrate Chk2-Interacting Zinc Finger ProteinAscizZinc Finger Protein 822 |
| Database Links | |
| Cellular Localisation | NucleusNuclearIn Discrete Foci During G1 Phase |
| Alternative Antibody Names | Anti-Atm Interactor antibodyAnti-Atm/Atr-Substrate Chk2-Interacting Zinc Finger Protein antibodyAnti-Asciz antibodyAnti-Zinc Finger Protein 822 antibodyAnti-ATMIN antibodyAnti-KIAA0431 antibodyAnti-ZNF822 antibody |
Information sourced from Uniprot.org