| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Autophagy-related protein 9B is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATG9B |
| Gene ID: |
285973 |
| Uniprot ID: |
ATG9B_HUMAN |
| Specificity: |
ATG9B Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Function | Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. In addition to autophagy, also plays a role in necrotic cell death. |
| Protein Name | Autophagy-Related Protein 9bApg9-Like 2Nitric Oxide Synthase 3-Overlapping Antisense Gene ProteinProtein Sone |
| Database Links | Reactome: R-HSA-1632852 |
| Cellular Localisation | Preautophagosomal Structure MembraneMulti-Pass Membrane ProteinUnder Amino Acid Starvation Or Rapamycin TreatmentRedistributes From A Juxtanuclear Clustered Pool To A Dispersed Peripheral Cytosolic PoolThe Starvation-Induced Redistribution Depends On Ulk1 And Atg13 |
| Alternative Antibody Names | Anti-Autophagy-Related Protein 9b antibodyAnti-Apg9-Like 2 antibodyAnti-Nitric Oxide Synthase 3-Overlapping Antisense Gene Protein antibodyAnti-Protein Sone antibodyAnti-ATG9B antibodyAnti-APG9L2 antibodyAnti-NOS3AS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
