| Host: |
Rabbit |
| Applications: |
IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Beclin 1-associated autophagy-related key regulator is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-300IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ATG14 |
| Gene ID: |
22863 |
| Uniprot ID: |
BAKOR_HUMAN |
| Specificity: |
The antibody detects endogenous ATG14L protein |
| Immunogen: |
Recombinant Protein of ATG14L |
| Protein Name | Beclin 1-Associated Autophagy-Related Key RegulatorBarkorAutophagy-Related Protein 14-Like ProteinAtg14l |
| Database Links | Reactome: R-HSA-1632852Reactome: R-HSA-9705671Reactome: R-HSA-983170 |
| Cellular Localisation | CytoplasmEndoplasmic Reticulum MembranePeripheral Membrane ProteinPreautophagosomal Structure MembraneCytoplasmic VesicleAutophagosome MembraneCytosolic Under Nutrient-Rich ConditionsFollowing Autophagy StimuliSuch As Starvation Or Rapamycin InductionPredominantly Detected In Cytoplasmic FociIdentified As Isolation Membranes And AutophagosomesAccumulates On Highly Curved Ptdins(3)P Enriched Autophagic Membrane Via Its Bats Domain To Sense And Maintain Membrane CurvatureLocalizes Also To Discrete Punctae Along The Ciliary Axoneme And To The Base Of The Ciliary Axoneme |
| Alternative Antibody Names | Anti-Beclin 1-Associated Autophagy-Related Key Regulator antibodyAnti-Barkor antibodyAnti-Autophagy-Related Protein 14-Like Protein antibodyAnti-Atg14l antibodyAnti-ATG14 antibodyAnti-ATG14L antibodyAnti-KIAA0831 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
