Anti-ATF3 antibody [R08-6H6] (STJA0035016)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human ATF3
General Information
| Short Description | Rabbit monoclonal anti-ATF3 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-6H6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | ATF3 |
| Gene ID | 467 |
| Uniprot ID | ATF3_HUMAN |
| Immunogen | Recombinant protein of human ATF3 |
Additional Info
| Function | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTACAG-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2: Activates transcription presumably by sequestering inhibitory cofactors away from the promoters. Isoform 3: Stress-induced isoform, counteracts the transcriptional repression of isoform 1. |
| Protein Name | Cyclic Amp-Dependent Transcription Factor Atf-3Camp-Dependent Transcription Factor Atf-3Activating Transcription Factor 3 |
| Database Links | Reactome: R-HSA-380994Reactome: R-HSA-9633012Reactome: R-HSA-9648895 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cyclic Amp-Dependent Transcription Factor Atf-3 antibodyAnti-Camp-Dependent Transcription Factor Atf-3 antibodyAnti-Activating Transcription Factor 3 antibodyAnti-ATF3 antibody |
Information sourced from Uniprot.org