Anti-ATF1 antibody [7F8] (STJ16103419)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenE.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1.
General Information
| Short Description | Mouse monoclonal anti-ATF1 for use in FC, IF, IHC, ICC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC/IF/IHC/ICC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 7F8 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | Adding 0.2 mL of distilled water =f 500 Mu g/mL. |
| Purification | Lyophilized |
| Formulation | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. NA |
| Storage Instruction | Store at-20°C for up to 1 year. Minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ATF1 |
| Gene ID | 466 |
| Uniprot ID | ATF1_HUMAN |
| Immunogen | E.coli-derived human ATF1 recombinant protein (Position: M1-V271). Human ATF1 shares 91% amino acid (aa) sequence identity with mouse ATF1. |
Additional Info
| Function | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTACAG-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. |
| Protein Name | Cyclic Amp-Dependent Transcription Factor Atf-1Camp-Dependent Transcription Factor Atf-1Activating Transcription Factor 1Protein Treb36 |
| Database Links | Reactome: R-HSA-199920Reactome: R-HSA-9031628 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cyclic Amp-Dependent Transcription Factor Atf-1 antibodyAnti-Camp-Dependent Transcription Factor Atf-1 antibodyAnti-Activating Transcription Factor 1 antibodyAnti-Protein Treb36 antibodyAnti-ATF1 antibody |
Information sourced from Uniprot.org