• Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-ATAD3A antibody (433-483 aa) (STJ194979)

SKU:
STJ194979

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ATPase family AAA domain-containing protein 3A (433-483 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATAD3A
Gene ID: 55210
Uniprot ID: ATD3A_HUMAN
Immunogen Region: 433-483 aa
Specificity: This antibody detects endogenous levels of ATD3A at Human
Immunogen: Synthesized peptide derived from the human ATD3A at the amino acid range 433-483
Function Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important role in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis. Involved in mitochondrial-mediated antiviral innate immunity.
Protein Name Atpase Family Aaa Domain-Containing Protein 3a
Cellular Localisation Mitochondrion Inner Membrane
Single-Pass Membrane Protein
Mitochondrion Matrix
Mitochondrion Nucleoid
In The Mitochondrial Inner Membrane
Enriched In Sites With The Potential To Form Contacts With The Outer Membrane
The N-Terminal Domain Interacts With The Inner Surface Of The Mitochondrial Outer Membrane And The C-Terminal Domain Localizes In A Specific Matrix Compartment
Where It Is Associated With Nucleoids
Alternative Antibody Names Anti-Atpase Family Aaa Domain-Containing Protein 3a antibody
Anti-ATAD3A antibody

Information sourced from Uniprot.org

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