Anti-ATAD1 antibody (STJA0004607)

SKU:
STJA0004607

Current Stock:
Host: Rabbit
Applications: IHC/ELISA
Reactivity: Human/Mouse/Rat
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Outer Mitochondrial Transmembrane Helix Translocase is suitable for use in Immunohistochemistry and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Concentration: 0.9 mg/mL
Dilution Range: IHC 1:40-1:200
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: ATAD1
Gene ID: 84896
Uniprot ID: ATAD1_HUMAN
Immunogen: Fusion protein of human ATAD1
Function Outer mitochondrial translocase required to remove mislocalized tail-anchored transmembrane proteins on mitochondria. Specifically recognizes and binds tail-anchored transmembrane proteins: acts as a dislocase that mediates the ATP-dependent extraction of mistargeted tail-anchored transmembrane proteins from the mitochondrion outer membrane. Also plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane.these activities are ATPase-dependent.
Protein Name Outer Mitochondrial Transmembrane Helix Translocase
Atpase Family Aaa Domain-Containing Protein 1
Hatad1
Thorase
Database Links Reactome: R-HSA-9603798
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Peroxisome Membrane
Postsynaptic Cell Membrane
Alternative Antibody Names Anti-Outer Mitochondrial Transmembrane Helix Translocase antibody
Anti-Atpase Family Aaa Domain-Containing Protein 1 antibody
Anti-Hatad1 antibody
Anti-Thorase antibody
Anti-ATAD1 antibody
Anti-FNP001 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance