| Short Description : | Mouse monoclonal anti-ASS1 for use in WB, IHC, ICC, IF and FC in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/ICC/IF/FC |
| Host: | Mouse |
| Reactivity: | Human/Mouse/Rat/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | 7I9 |
| Isotype: | IgG2b |
| Conjugation: | Unconjugated |
| Concentration: | Adding 0.2 mL of distilled water =f 500 Mu g/mL. |
| Purification: | Lyophilized |
| Formulation: | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. NA |
| Storage Instruction: | Store at-20°C for up to 1 year. Minimise freeze-thaw cycles. |
| Gene Symbol: | ASS1 |
| Gene ID: | 445 |
| Uniprot ID: | ASSY_HUMAN |
| Immunogen: | E.coli-derived human ASS1 recombinant protein (Position: S3-S365). |
| Post Translational Modifications | Acetylated by CLOCK in a circadian manner which negatively regulates its enzyme activity. Deacetylated by histone deacetylases. |
| Function | One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. |
| Protein Name | Argininosuccinate SynthaseCitrulline--Aspartate Ligase |
| Database Links | Reactome: R-HSA-70635 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Argininosuccinate Synthase antibodyAnti-Citrulline--Aspartate Ligase antibodyAnti-ASS1 antibodyAnti-ASS antibody |
Information sourced from Uniprot.org
