Anti-Aspartate Aminotransferase antibody [R09-9G8] (STJA0034297)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human FABP-1
General Information
| Short Description | Rabbit monoclonal anti-Aspartate Aminotransferase for use in WB, IHC-P and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R09-9G8 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | GOT2 |
| Gene ID | 2806 |
| Uniprot ID | AATM_HUMAN |
| Immunogen | A synthetic peptide of human FABP-1 |
Additional Info
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
| Protein Name | Aspartate Aminotransferase - MitochondrialMaspatFatty Acid-Binding ProteinFabp-1Glutamate Oxaloacetate Transaminase 2Kynurenine Aminotransferase 4Kynurenine Aminotransferase IvKynurenine--Oxoglutarate Transaminase 4Kynurenine--Oxoglutarate Transaminase IvPlasma Membrane-Associated Fatty Acid-Binding ProteinFabppmTransaminase A |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-389661Reactome: R-HSA-8963693Reactome: R-HSA-8964539Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion MatrixCell MembraneExposure To Alcohol Promotes Translocation To The Cell Membrane |
| Alternative Antibody Names | Anti-Aspartate Aminotransferase - Mitochondrial antibodyAnti-Maspat antibodyAnti-Fatty Acid-Binding Protein antibodyAnti-Fabp-1 antibodyAnti-Glutamate Oxaloacetate Transaminase 2 antibodyAnti-Kynurenine Aminotransferase 4 antibodyAnti-Kynurenine Aminotransferase Iv antibodyAnti-Kynurenine--Oxoglutarate Transaminase 4 antibodyAnti-Kynurenine--Oxoglutarate Transaminase Iv antibodyAnti-Plasma Membrane-Associated Fatty Acid-Binding Protein antibodyAnti-Fabppm antibodyAnti-Transaminase A antibodyAnti-GOT2 antibodyAnti-KYAT4 antibody |
Information sourced from Uniprot.org