Anti-ASIC2 antibody (450-512) {Biotin} (STJ500175)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
IsotypeIgG
ImmunogenSynthetic peptide taken within amino acid region 450-512 on human Acid-sensing ion channel 2 protein.
General Information
| Short Description | Rabbit polyclonal antibody anti-ASIC2 (450-512) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Applications | ELISA/IP/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Biotin |
| Concentration | 0.5-1.5 µg/µl |
| Purification | Affinity Purified |
| Dilution Range | WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200 |
| Formulation | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | ASIC2 |
| Gene ID | 40 |
| Uniprot ID | ASIC2_HUMAN |
| Immunogen | Synthetic peptide taken within amino acid region 450-512 on human Acid-sensing ion channel 2 protein. |
| Immunogen Region | 450-512 |
Additional Info
| Tissue Specificity | Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary. |
| Function | Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. |
| Protein Name | Acid-Sensing Ion Channel 2Asic2Amiloride-Sensitive Brain Sodium ChannelAmiloride-Sensitive Cation Channel 1 - NeuronalAmiloride-Sensitive Cation Channel Neuronal 1Brain Sodium Channel 1Bnc1Bnac1Mammalian Degenerin HomologMdeg |
| Database Links | Reactome: R-HSA-2672351 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized At The Plasma Membrane Of NeuronsIn The Soma And Punctated Peripheral Processes |
| Alternative Antibody Names | Anti-Acid-Sensing Ion Channel 2 antibodyAnti-Asic2 antibodyAnti-Amiloride-Sensitive Brain Sodium Channel antibodyAnti-Amiloride-Sensitive Cation Channel 1 - Neuronal antibodyAnti-Amiloride-Sensitive Cation Channel Neuronal 1 antibodyAnti-Brain Sodium Channel 1 antibodyAnti-Bnc1 antibodyAnti-Bnac1 antibodyAnti-Mammalian Degenerin Homolog antibodyAnti-Mdeg antibodyAnti-ASIC2 antibodyAnti-ACCN antibodyAnti-ACCN1 antibodyAnti-BNAC1 antibodyAnti-MDEG antibody |
Information sourced from Uniprot.org