Anti-ASGR2 antibody [SRM14903] (STJ11109633)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal ASGR2 antibody for use in WB, IF-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14903 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:2000-1:10000IF-P, 1:50-1:200ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ASGR2 |
| Gene ID | 433 |
| Uniprot ID | ASGR2_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Expressed exclusively in hepatic parenchymal cells. |
| Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
| Protein Name | Asialoglycoprotein Receptor 2Asgp-R 2Asgpr 2C-Type Lectin Domain Family 4 Member H2Hepatic Lectin H2Hl-2 |
| Database Links | Reactome: R-HSA-446203 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Asialoglycoprotein Receptor 2 antibodyAnti-Asgp-R 2 antibodyAnti-Asgpr 2 antibodyAnti-C-Type Lectin Domain Family 4 Member H2 antibodyAnti-Hepatic Lectin H2 antibodyAnti-Hl-2 antibodyAnti-ASGR2 antibodyAnti-CLEC4H2 antibody |
Information sourced from Uniprot.org