Anti-ASGPR antibody [R05-6M-1] (STJA0033733)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenPeptide
General Information
| Short Description | Rabbit monoclonal anti-ASGPR for use in WB, IHC-P, ICC, IF, FC and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/FC/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-6M-1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Protein A |
| Dilution Range | WB 1:500-1:1000IHC-P 1:50-1:100ICC:IF 1:50FC 1:50-1:100 |
| Formulation | Liquid in PBS, Glycerol and BSA |
| Storage Instruction | Store at-20°C. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | ASGR1 |
| Gene ID | 432 |
| Uniprot ID | ASGR1_HUMAN |
| Immunogen | Peptide |
Additional Info
| Tissue Specificity | Expressed exclusively in hepatic parenchymal cells. |
| Post Translational Modifications | Phosphorylated on a cytoplasmic Ser residue. |
| Function | Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. |
| Protein Name | Asialoglycoprotein Receptor 1Asgp-R 1Asgpr 1C-Type Lectin Domain Family 4 Member H1Hepatic Lectin H1Hl-1 |
| Database Links | Reactome: R-HSA-446203 |
| Cellular Localisation | Isoform H1a: MembraneSingle-Pass Type Ii Membrane ProteinIsoform H1b: Secreted |
| Alternative Antibody Names | Anti-Asialoglycoprotein Receptor 1 antibodyAnti-Asgp-R 1 antibodyAnti-Asgpr 1 antibodyAnti-C-Type Lectin Domain Family 4 Member H1 antibodyAnti-Hepatic Lectin H1 antibodyAnti-Hl-1 antibodyAnti-ASGR1 antibodyAnti-CLEC4H1 antibody |
Information sourced from Uniprot.org