Anti-ASF1B IP antibody [SAA0242] (STJA0018757)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
General Information
| Short Description | Mouse monoclonal Histone Chaperone Asf1b antibody for use in ELISA, IF and IP in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IF/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0242 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | ASF1B |
| Gene ID | 55723 |
| Uniprot ID | ASF1B_HUMAN |
Additional Info
| Post Translational Modifications | Phosphorylated by TLK1 and TLK2. |
| Function | Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' (H3K9me1) and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5K12ac) marks in the cytosol. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for gonad development. |
| Protein Name | Histone Chaperone Asf1bAnti-Silencing Function Protein 1 Homolog BHasf1Hasf1bCcg1-Interacting Factor A-IiCia-IiHcia-Ii |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytosol |
| Alternative Antibody Names | Anti-Histone Chaperone Asf1b antibodyAnti-Anti-Silencing Function Protein 1 Homolog B antibodyAnti-Hasf1 antibodyAnti-Hasf1b antibodyAnti-Ccg1-Interacting Factor A-Ii antibodyAnti-Cia-Ii antibodyAnti-Hcia-Ii antibodyAnti-ASF1B antibody |
Information sourced from Uniprot.org