Anti-Ascl3-Mouse antibody (Internal) (STJ72471)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Ascl3-Mouse (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 23kDa band observed in Mouse Liver lysates (calculated MW of 20.2kDa according to NP_064435.1). Recommended concentration: 0.1-0.3µg/ml. Primary incubation was 1 hour.IHC: P |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ASCL3 |
| Gene ID | 56676 |
| Uniprot ID | ASCL3_HUMAN |
| Accession Number | NP_064435.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | HLPEDYLEKRLSK |
Additional Info
| Function | Transcriptional repressor. Inhibits myogenesis. Plays a role in progenitor cells which differentiate into ductal and acinar, but not myoepithelial, cell lineages in the salivary glands. Involved in the functions of the microvillar cells and Bowman's glands and probably, in a non-cell-autonomous manner, in the development or regeneration of a complete olfactory epithelium (OE). |
| Protein Name | Achaete-Scute Homolog 3Ash-3Hash3Class A Basic Helix-Loop-Helix Protein 42Bhlha42Bhlh Transcriptional Regulator Sgn-1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Achaete-Scute Homolog 3 antibodyAnti-Ash-3 antibodyAnti-Hash3 antibodyAnti-Class A Basic Helix-Loop-Helix Protein 42 antibodyAnti-Bhlha42 antibodyAnti-Bhlh Transcriptional Regulator Sgn-1 antibodyAnti-ASCL3 antibodyAnti-BHLHA42 antibodyAnti-HASH3 antibodyAnti-SGN1 antibody |
Information sourced from Uniprot.org