Anti-ASAP2 antibody (1-120) (STJ119651)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ASAP2 (1-120) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ASAP2 |
| Gene ID | 8853 |
| Uniprot ID | ASAP2_HUMAN |
| Immunogen Region | 1-120 |
| Immunogen Sequence | MPDQISVSEFVAETHEDYKA PTASSFTTRTAQCRNTVAAI EEALDVDRMVLYKMKKSVKA INSSGLAHVENEEQYTQALE KFGGNCVCRDDPDLGSAFLK FSVFTKELTALFKNLIQNMN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human ASAP2 (NP_001128663). |
Additional Info
| Tissue Specificity | Detected in heart, brain, placenta, kidney, monocytes and pancreas. |
| Post Translational Modifications | Phosphorylated on tyrosine residues by SRC and PTK2B. |
| Function | Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. |
| Protein Name | Arf-Gap With Sh3 Domain - Ank Repeat And Ph Domain-Containing Protein 2Development And Differentiation-Enhancing Factor 2Paxillin-Associated Protein With Arf Gap Activity 3Pag3Pyk2 C-Terminus-Associated ProteinPap |
| Database Links | |
| Cellular Localisation | CytoplasmGolgi ApparatusGolgi Stack MembranePeripheral Membrane ProteinCell MembraneColocalizes With F-Actin And Arf6 In Phagocytic Cups |
| Alternative Antibody Names | Anti-Arf-Gap With Sh3 Domain - Ank Repeat And Ph Domain-Containing Protein 2 antibodyAnti-Development And Differentiation-Enhancing Factor 2 antibodyAnti-Paxillin-Associated Protein With Arf Gap Activity 3 antibodyAnti-Pag3 antibodyAnti-Pyk2 C-Terminus-Associated Protein antibodyAnti-Pap antibodyAnti-ASAP2 antibodyAnti-DDEF2 antibodyAnti-KIAA0400 antibody |
Information sourced from Uniprot.org