Anti-Arylsulfatase B antibody (Internal) (STJ71319)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Arylsulfatase B (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 45kDa band observed in Human Heart lysates (calculated MW of 46.0kDa according to NP_942002.1). Recommended concentration: 0.03-0.1µg/ml.An additional band of unknown identity w |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | ARSB |
| Gene ID | 411 |
| Uniprot ID | ARSB_HUMAN |
| Accession Number | NP_000037.2; NP_942002.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | KLARGHTNGTKPLD |
| Specificity | This antibody is expected to recognise both reported isoforms (NP_000037.2; NP_942002.1). |
Additional Info
| Function | Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels. |
| Protein Name | Arylsulfatase BAsbN-Acetylgalactosamine-4-SulfataseG4s |
| Database Links | Reactome: R-HSA-1663150Reactome: R-HSA-2024101Reactome: R-HSA-2206285Reactome: R-HSA-6798695Reactome: R-HSA-9840310 |
| Cellular Localisation | LysosomeCell Surface |
| Alternative Antibody Names | Anti-Arylsulfatase B antibodyAnti-Asb antibodyAnti-N-Acetylgalactosamine-4-Sulfatase antibodyAnti-G4s antibodyAnti-ARSB antibody |
Information sourced from Uniprot.org