Anti-ARVCF antibody (1-100 aa) (STJ11106576)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ARVCF (1-100 aa) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARVCF |
| Gene ID | 421 |
| Uniprot ID | ARVC_HUMAN |
| Immunogen Region | 1-100 aa |
| Immunogen Sequence | MEDCNVHSAASILASVKEQE ARFERLTRALEQERRHVALQ LERAQQPGMVSGGMGSGQPL PMAWQQLVLQEQSPGSQASL ATMPEAPDVLEETVTVEEDP |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARVCF (NP_001661.1). |
Additional Info
| Tissue Specificity | Found in all the examined tissues including heart, brain, liver and kidney. Found at low level in lung. Expressed in dermal connective tissue, salivary gland duct and in the corneal layer (at protein level). Expressed in arrector pili muscle (at protein level). High levels detected in epithelial cells with lower levels found in fibroblasts and T lymphocytes. |
| Function | Contributes to the regulation of alternative splicing of pre-mRNAs. |
| Protein Name | Splicing Regulator ArvcfArmadillo Repeat Protein Deleted In Velo-Cardio-Facial Syndrome |
| Database Links | |
| Cellular Localisation | Cell JunctionAdherens JunctionNucleusCytoplasmIn HeartLocalizes At Area CompositaThe Mixed-Type Junctional Structure Composed Of Both Desmosomal And Adherens Junctional Proteins |
| Alternative Antibody Names | Anti-Splicing Regulator Arvcf antibodyAnti-Armadillo Repeat Protein Deleted In Velo-Cardio-Facial Syndrome antibodyAnti-ARVCF antibody |
Information sourced from Uniprot.org