Anti-ARL4C antibody (STJA0006973)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ARL4C
General Information
| Short Description | Rabbit polyclonal anti-ADP-ribosylation factor-like protein 4C for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARL4C |
| Gene ID | 10123 |
| Uniprot ID | ARL4C_HUMAN |
| Immunogen | Synthesized peptide derived from human ARL4C |
| Specificity | This antibody detects endogenous levels of ARL4C at Human, Mouse |
Additional Info
| Function | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process. |
| Protein Name | Adp-Ribosylation Factor-Like Protein 4cAdp-Ribosylation Factor-Like Protein 7Adp-Ribosylation Factor-Like Protein Lak |
| Database Links | Reactome: R-HSA-9029569 |
| Cellular Localisation | Cell ProjectionFilopodiumCell MembraneCytoplasm |
| Alternative Antibody Names | Anti-Adp-Ribosylation Factor-Like Protein 4c antibodyAnti-Adp-Ribosylation Factor-Like Protein 7 antibodyAnti-Adp-Ribosylation Factor-Like Protein Lak antibodyAnti-ARL4C antibodyAnti-ARL7 antibody |
Information sourced from Uniprot.org