| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADP-ribosylation factor-like protein 13B is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ARL13B |
| Gene ID: |
200894 |
| Uniprot ID: |
AR13B_HUMAN |
| Specificity: |
This antibody detects endogenous levels of ARL13B at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human ARL13B |
| Post Translational Modifications | Sumoylation is required for PKD2 entry into cilium. |
| Function | Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it.the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex. May regulate endocytic recycling traffic.however, additional evidence is required to confirm these data. |
| Protein Name | Adp-Ribosylation Factor-Like Protein 13bAdp-Ribosylation Factor-Like Protein 2-Like 1Arl2-Like Protein 1 |
| Database Links | Reactome: R-HSA-5624958Reactome: R-HSA-9013406Reactome: R-HSA-9013409Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9646399 |
| Cellular Localisation | Cell ProjectionCilium MembraneLipid-AnchorCiliumAssociates To The Cilium Membrane Via PalmitoylationLocalizes To Proximal Ciliary MembranesTo An Inversin-Like Subciliary Membrane CompartmentExcluding The Transition Zone |
| Alternative Antibody Names | Anti-Adp-Ribosylation Factor-Like Protein 13b antibodyAnti-Adp-Ribosylation Factor-Like Protein 2-Like 1 antibodyAnti-Arl2-Like Protein 1 antibodyAnti-ARL13B antibodyAnti-ARL2L1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
