Anti-ARHU/WRCH1 antibody (N-Term) (STJ70145)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-ARHU/WRCH1 (N-Term) is suitable for use in ELISA research applications. |
| Applications | Pep-ELISA |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx. 22kDa band in lysates of cell lines A431, HeLa and HEK293 after 0.3µg/ml antibody staining. Please note that currently we cannot find an explana |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | RHOU |
| Gene ID | 58480 |
| Uniprot ID | RHOU_HUMAN |
| Accession Number | NP_067028.1 |
| Immunogen Region | N-Term |
| Immunogen Sequence | PPQQGDPAFPDRCEA |
Additional Info
| Post Translational Modifications | Tyrosine phosphorylated by SRC in response to PTK2B/PYK2 activation. |
| Function | Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. |
| Protein Name | Rho-Related Gtp-Binding Protein RhouCdc42-Like Gtpase 1Gtp-Binding Protein-Like 1Rho Gtpase-Like Protein ArhuRyu GtpaseWnt-1 Responsive Cdc42 Homolog 1Wrch-1 |
| Database Links | Reactome: R-HSA-6785807Reactome: R-HSA-9013420 |
| Cellular Localisation | Cell MembraneLipid-AnchorCytoplasmic SideGolgi Apparatus MembraneCell JunctionFocal AdhesionCell ProjectionPodosomeLocalizes To Podosomes In Src-Transformed Cells |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rhou antibodyAnti-Cdc42-Like Gtpase 1 antibodyAnti-Gtp-Binding Protein-Like 1 antibodyAnti-Rho Gtpase-Like Protein Arhu antibodyAnti-Ryu Gtpase antibodyAnti-Wnt-1 Responsive Cdc42 Homolog 1 antibodyAnti-Wrch-1 antibodyAnti-RHOU antibodyAnti-ARHU antibodyAnti-CDC42L1 antibodyAnti-G28K antibodyAnti-WRCH1 antibodyAnti-SB128 antibody |
Information sourced from Uniprot.org