| Short Description : | Rabbit polyclonal anti-Rho GDP-dissociation inhibitor 3 (110-190 aa) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARHGDIG |
| Gene ID: | 398 |
| Uniprot ID: | GDIR3_HUMAN |
| Immunogen: | Synthesized peptide derived from Rho GDI Gamma at the amino acid range 110-190 |
| Immunogen Region: | 110-190 aa |
| Specificity: | Rho GDI Gamma Polyclonal Antibody detects endogenous levels of Rho GDI Gamma protein. |
| Function | Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP. |
| Protein Name | Rho Gdp-Dissociation Inhibitor 3Rho Gdi 3Rho-Gdi Gamma |
| Database Links | Reactome: R-HSA-9013026Reactome: R-HSA-9013148Reactome: R-HSA-9013407Reactome: R-HSA-9013408 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Rho Gdp-Dissociation Inhibitor 3 antibodyAnti-Rho Gdi 3 antibodyAnti-Rho-Gdi Gamma antibodyAnti-ARHGDIG antibody |
Information sourced from Uniprot.org
