| Short Description : | Rabbit polyclonal ARHGDIB (1-201) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARHGDIB |
| Gene ID: | 397 |
| Uniprot ID: | GDIR2_HUMAN |
| Immunogen Region: | 1-201 |
| Immunogen Sequence: | MTEKAPEPHVEEDDDDELDS KLNYKPPPQKSLKELQEMDK DDESLIKYKKTLLGDGPVVT DPKAPNVVVTRLTLVCESAP GPITMDLTGDLEALKKETIV LKEGSEYRVKIHFKVNRDIV SGLKYVQHTYRTGVKVDKAT FMVGSYGPRPEEYEFLTPVE EAPKGMLARGTYHNKSFFTD DDKQDHLSWEWNLSIKKEWT E |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human ARHGDIB (NP_001166.3). |
| Tissue Specificity | Detected in bone marrow, thymus and spleen. |
| Function | Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Regulates reorganization of the actin cytoskeleton mediated by Rho family members. |
| Protein Name | Rho Gdp-Dissociation Inhibitor 2Rho Gdi 2Ly-GdiRho-Gdi Beta |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013407Reactome: R-HSA-9013408Reactome: R-HSA-9013423 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Rho Gdp-Dissociation Inhibitor 2 antibodyAnti-Rho Gdi 2 antibodyAnti-Ly-Gdi antibodyAnti-Rho-Gdi Beta antibodyAnti-ARHGDIB antibodyAnti-GDIA2 antibodyAnti-GDID4 antibodyAnti-RAP1GN1 antibody |
Information sourced from Uniprot.org
