Anti-ARHGDIB antibody (1-201) (STJ22676)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ22676
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General Information

Short DescriptionRabbit polyclonal ARHGDIB (1-201) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolARHGDIB
Gene ID397
Uniprot IDGDIR2_HUMAN
Immunogen Region1-201
Immunogen SequenceMTEKAPEPHVEEDDDDELDS KLNYKPPPQKSLKELQEMDK DDESLIKYKKTLLGDGPVVT DPKAPNVVVTRLTLVCESAP GPITMDLTGDLEALKKETIV LKEGSEYRVKIHFKVNRDIV SGLKYVQHTYRTGVKVDKAT FMVGSYGPRPEEYEFLTPVE EAPKGMLARGTYHNKSFFTD DDKQDHLSWEWNLSIKKEWT E
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human ARHGDIB (NP_001166.3).

Additional Info

Tissue Specificity Detected in bone marrow, thymus and spleen.
Function Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Regulates reorganization of the actin cytoskeleton mediated by Rho family members.
Protein Name Rho Gdp-Dissociation Inhibitor 2
Rho Gdi 2
Ly-Gdi
Rho-Gdi Beta
Database Links Reactome: R-HSA-8980692
Reactome: R-HSA-9013148
Reactome: R-HSA-9013149
Reactome: R-HSA-9013407
Reactome: R-HSA-9013408
Reactome: R-HSA-9013423
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Rho Gdp-Dissociation Inhibitor 2 antibody
Anti-Rho Gdi 2 antibody
Anti-Ly-Gdi antibody
Anti-Rho-Gdi Beta antibody
Anti-ARHGDIB antibody
Anti-GDIA2 antibody
Anti-GDID4 antibody
Anti-RAP1GN1 antibody

Information sourced from Uniprot.org

Citations

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