Anti-ARHGAP5 antibody (1150-1300) [S4MR] (STJ11101814)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal RhoGAP (1150-1300) antibody for use in WB, IP and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IP:0.5 Mu g-4 Mu g antibody for 400 Mu g-600 Mu g extracts of whole cellsELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARHGAP5 |
| Gene ID | 394 |
| Uniprot ID | RHG05_HUMAN |
| Immunogen Region | 1150-1300 |
| Immunogen Sequence | PSKYKYKSKTLFSKAKSYYR RTHSDASDDEAFTTSKTKRK GRHRGSEEDPLLSPVETWKG GIDNPAITSDQELDDKKMKK KTHKVKEDKKQKKKTKNFNP PTRRNWESNYFGMPLQDLVT AEKPIPLFVEKCVEFIEDTG LCTEGLYRVSG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1150-1300 of human RhoGAP (Q13017). |
Additional Info
| Tissue Specificity | Detected in skin fibroblasts (at protein level). |
| Function | GTPase-activating protein for Rho family members. |
| Protein Name | Rho Gtpase-Activating Protein 5Rho-Type Gtpase-Activating Protein 5P190-B |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013149Reactome: R-HSA-9013405Reactome: R-HSA-9013406Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423Reactome: R-HSA-9035034Reactome: R-HSA-9696264Reactome: R-HSA-9696270Reactome: R-HSA-9696273 |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinAlso Membrane-Associated In A Fibrillar Pattern That Colocalizes With The Alpha5-Beta1 Integrin Receptor (Itga5/Itgb1) For Fibronectin |
| Alternative Antibody Names | Anti-Rho Gtpase-Activating Protein 5 antibodyAnti-Rho-Type Gtpase-Activating Protein 5 antibodyAnti-P190-B antibodyAnti-ARHGAP5 antibodyAnti-RHOGAP5 antibody |
Information sourced from Uniprot.org