| Short Description : | Rabbit polyclonal ARHGAP4 (900 aa) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ARHGAP4 |
| Gene ID: | 393 |
| Uniprot ID: | RHG04_HUMAN |
| Immunogen Region: | 900 aa |
| Immunogen Sequence: | SPEQHVEVDKAVAQNMDSVF KELLGKTSVRQGLGPASTTS PSPGPRSPKAPPSSRLGRNK GFSRGPGAPASPSASHPQGL DTTPKPH |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human ARHGAP4 (NP_001158213.1). |
| Tissue Specificity | Predominantly in hematopoietic cells (spleen, thymus and leukocytes).low levels in placenta, lung and various fetal tissues. |
| Function | Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells. |
| Protein Name | Rho Gtpase-Activating Protein 4Rho-Gap Hematopoietic Protein C1Rho-Type Gtpase-Activating Protein 4P115 |
| Database Links | Reactome: R-HSA-8980692Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
| Cellular Localisation | CytoplasmJust Below The Plasma Membrane |
| Alternative Antibody Names | Anti-Rho Gtpase-Activating Protein 4 antibodyAnti-Rho-Gap Hematopoietic Protein C1 antibodyAnti-Rho-Type Gtpase-Activating Protein 4 antibodyAnti-P115 antibodyAnti-ARHGAP4 antibodyAnti-KIAA0131 antibodyAnti-RGC1 antibodyAnti-RHOGAP4 antibody |
Information sourced from Uniprot.org
